"芯片有效面积≥1cm*1cm,区域内包含≥4 亿个空间点,每个空间点直径≤0.22um,点和点之间中心距离≤0.5um。测序rawdata数据量≥1G reads/样,Q30>80%。
Chip effective area ≥ 1cm*1cm and the area contains ≥ 400 million spatial points, each spatial point diameter ≤ 0.22um, and the center distance between points ≤ 0.5um. The amount of sequencing rawdata data ≥ 1G reads/sample, Q30>80%."
"基于DNA纳米球(DNA Nano Ball,DNB)开发,是具有高通量、超高分辨率、大视场的原位全景式技术,可以实现同一样本在组织、细胞、亚细胞、分子“四尺度”同时进行空间转录组分析。该技术通过时空芯片捕获组织中的mRNA,并通过时空条形码(Coordinate ID,CID)还原回空间位置,实现组织原位测序,为深入地了解细胞的基因表达及形态与局部环境之间的关系建立强大的研究基础。
STOmics proprietary Stereo-seq (SpaTial Enhanced REsolution Omics-sequencing) technology offers researchers a novel tool to explore spatial biology with unprecedented field-of-view, and subcellular resolution, enabling simultaneous transcriptome study and analysis at tissue-, cellular-, subcellular- and molecular level from fresh frozen tissue. Stereo-seq captures mRNA within the tissue on the chip and restores cellular spatial location through spatial coordination barcoding (Coordinate ID, CID), realizing in situ sequencing of tissues for establishing a strong research foundation for in-depth understanding of the relationship among gene expression, cell morphology and cellular microenvironments."
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