1、Octet®系统使用非标记的生物层干涉 (BLI) 技术,提供快速、稳定且无流路的生物分子分析方法;2、22种光纤生物传感器:即用型,无流路;3、检测通道:8通道平行检测,同时检测8组独立的生物分子相互作用,通道可以灵活控制;4、结合速率范围(ka): 101 ~ 107 M-1S-1;5、解离速率范围(kd): 10-6 ~ 10 -1S-1;6、检测分子量下限:150 Da;7、亲和力 (KD) 范围 mM – pM;8、温度控制 15°C–40°C;9、振荡速度 0-1500 rpm; 1、Based on Bio-Layer Interferometry (BLI), Octet® BLI systems enable fluidic-free,real-time, label-free analysis for the determination of kinetics, affinity and antibody/protein quantitation ; 2、Fiber optic biosensors :ready-to-use with a fluidics-free design; 3、Analysis can be done using a single channel or up to eight channels, enabling flexibility in sample throughput.4、Association Rate Constant (ka):101 to 107 M-1 s-1 ;5、Dissociation Rate Constant (kd) :10-6 to 10-1 s-1 ;6、Molecular Weight Detection>150 Da; 7、Affinity Constant (KD):1 mM – 10 pM;8、Analysis Temperature Range:15°C to 40°C, in 1°C increments; 9、Orbital Flow Capacity:Static or 100–1500 rpm
Octet® R8系统可用于广泛的分析,包括动力学分析、IgG和其他蛋白质的滴度、试剂鉴定、免疫测定开发、生物工艺开发、质量分析、抗体筛选、表位合并/定位、配体结合测定、小分子分析、阐明细胞信号传导机制和传染病监测。 The Octet® R8 system can be used for a wide range of analyses including kinetic analysis, titer of IgG and other proteins, reagent qualification, immunoassay development, bioprocess development, quality analysis, crude antibody screening, epitope binning/mapping, ligand binding assays, small molecule analysis, elucidating cell signaling mechanisms, and infectious disease monitoring.
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